Yianni
Psaltis , PhD

Entrepreneur, investor, and advisor at the confluence of AI and healthspan.

"Not just moonshots, moon landings."

Dr. Yianni Psaltis
As Featured At
Aging Research &
Drug Discovery Meeting (ARDD)
Longevity Docs XPRIZE Healthspan
Investor's Summit
Future Investment
Initiative (FII)

"Where science meets imagination — conviction follows."

Dr. Yianni Psaltis
About

A deep-seated faith in the transformative capacities of science and art alike — I advocate for their dual roles in addressing the most pressing challenges our world faces.

My approach to business and life is galvanized by a relentless immigrant mentality — an unfaltering work ethic paired with an ethical compass and a creative audacity. I am a believer in the emancipating powers of imagination, which affords a temporary pass to interrogate entrenched perspectives of the world, fueling the conversion of simple observations into unprecedented discoveries.

Traversing executive strategy, venture capital, and technology innovation, my professional repertoire serves as a bedrock to engage with organizations and founders alike — helping them navigate the anfractuous terrain of exponential technology and uncover fresh avenues for growth. At Link Ventures, I helped establish and launch the Link-XPV Fund, an early-stage vehicle investing primarily in enterprise AI out of the Boston ecosystem alongside Peter Diamandis and Dave Blundin. Before that, I served as the "Strike Force" Entrepreneur-in-Residence alongside futurist Dr. Peter H. Diamandis, operating as strategic counsel, board observer, and intellectual collaborator.

Working at the confluence of AI and other exponential technologies, a key focus area is to pioneer developments in the arena of healthy aging and human longevity. As I find myself at this remarkable nexus of technologies, my ambition is to significantly influence the global health trajectory, making a substantial, enduring impact on citizens worldwide.

"Not just moonshots, moon landings."

"Compounding intelligence against compounding time."

Investment
Thesis

Areas of conviction
001

Longevity Biosciences

Therapeutics, diagnostics, and platforms extending human healthspan — from senolytics and epigenetic reprogramming to novel biomarker discovery. Confronting the inexorable movement of time with science.

002

Applied AI

Infrastructure and applications where machine intelligence compounds domain-specific value. Not disposable pleasure but meaningful pursuit — models that do, not just predict, with durable moats.

003

Data & Exponential Tech

The pipes, protocols, and platforms that make the first two possible. Nodes within a network of nodes — data as the substrate for compounding intelligence and scientific progress.

Portfolio

Investments & Advisory
Investments
Advisory

Select investments and advisory positions. Inclusion does not constitute an endorsement or solicitation.

"From observation, to narrative — to culture-defining companies and movements."

The Path

Career
On stage with Peter Diamandis

On stage with Dr. Peter H. Diamandis — Abundance Longevity Trip

Present Managing Director

Link Ventures

A key component of the founding team that launched Link Ventures' 4th fund, Link-Exponential Ventures ("Link-XPV") ($200M+), alongside Peter Diamandis and Dave Blundin — an early-stage vehicle investing primarily in enterprise AI out of the Boston ecosystem. The fund operates with an accompanying venture studio, with approximately 75% of investments emerging from Harvard and MIT. Early checks in companies like Mercor, Blitzy, and Ornn. Providing deep hands-on support to founders across the portfolio, with platform support including the Moonshots podcast — one of the fastest-growing tech podcasts — and presence at international stages including the World Economic Forum, FII, and other key events.

Previous "Strike Force" EIR

PHD Ventures — Dr. Peter H. Diamandis

Dr. Diamandis' primary thought partner — strategic counsel, board observer, and intellectual collaborator. Instrumental in launching the XPRIZE Healthspan competition, contributing to prize development, playing a critical role in raising $157M alongside Dr. Diamandis, and identifying the Executive Director who built out a world-class team. Co-curator of Abundance Longevity Trips, an exclusive experience featuring the world's top health and longevity companies. Supported the early development of Fountain Life, a longevity diagnostics and therapeutics clinic network co-founded by Peter Diamandis and Tony Robbins, with backing from leaders including Marc Benioff.

With Peter Diamandis and Dr. Matt Walker at Abundance Longevity Trip

With Peter Diamandis and Dr. Matt Walker — Abundance Longevity Trip

Foundation MS, Biotechnology & PhD, Cancer Biology

Georgetown University

Doctoral research at the intersection of cellular biology, biochemistry, and translational science — the foundation for an interdisciplinary approach to investing at the nexus of AI and longevity.

Presenting at Georgetown University

Presenting at Georgetown University

Connect.

For investment inquiries, partnerships, or speaking engagements.